Mixed-function oxidase studies in the redfish, sciaenops ocellata, from galveston bay, texas

Cynthia Hung Stahl; Lester G. Sultatos; Carl S. Hacker; Sheldon D. Murphy

doi:10.1016/0742-8413(84)90182-8

Mixed-function oxidase studies in the redfish, sciaenops ocellata, from galveston bay, texas

Cynthia Hung Stahl
, Lester G. Sultatos
, Carl S. Hacker
, Sheldon D. Murphy

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

1. The metabolism of parathion to para-nitrophenol (PNP) in redfish (Sciaenops ocellata) liver microsomes has been both identified and characterized. 2. This mixed-function oxidase (MFO) reaction in redfish requires NADPH and is inhibited by carbon monoxide. It exhibits a temperature optimum of 25°C but no clear pH optimum between 7.0-8.5. 3. Redfish hepatic microsomal MFOs were not induced by 2.5 days after a single i.p. injection of 88 mg Aroclor 1254/kg body wt, but under the same dosage and time conditions male albino Swiss mice were significantly induced (p < 0.05).

Original language	English (US)
Pages (from-to)	177-182
Number of pages	6
Journal	Comparative Biochemistry and Physiology. Part C, Comparative
Volume	79
Issue number	1
DOIs	https://doi.org/10.1016/0742-8413(84)90182-8
State	Published - 1984
Externally published	Yes

All Science Journal Classification (ASJC) codes

Immunology
Pharmacology

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10.1016/0742-8413(84)90182-8

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@article{185130593aa2414e9228e771380fe6b2,

title = "Mixed-function oxidase studies in the redfish, sciaenops ocellata, from galveston bay, texas",

abstract = "1. The metabolism of parathion to para-nitrophenol (PNP) in redfish (Sciaenops ocellata) liver microsomes has been both identified and characterized. 2. This mixed-function oxidase (MFO) reaction in redfish requires NADPH and is inhibited by carbon monoxide. It exhibits a temperature optimum of 25°C but no clear pH optimum between 7.0-8.5. 3. Redfish hepatic microsomal MFOs were not induced by 2.5 days after a single i.p. injection of 88 mg Aroclor 1254/kg body wt, but under the same dosage and time conditions male albino Swiss mice were significantly induced (p < 0.05).",

author = "Stahl, \{Cynthia Hung\} and Sultatos, \{Lester G.\} and Hacker, \{Carl S.\} and Murphy, \{Sheldon D.\}",

note = "Funding Information: \textasciitilde{}c\textasciitilde{}\textasciitilde{}o\textasciitilde{}\textasciitilde{}e\textasciitilde{}g\textasciitilde{}\textasciitilde{}e{\~a}u\textasciitilde{}th-oTrhwse o uldli ke to exprestsh eir appreciatiofonr theh elpg iven by the members of the Texas Department of Parks and Wildlife at Seabrook, Texas, especially Bill Baker. The organisms were collected under the Texas Department of Parks and Wildlife scientific Permit number 86. This work was supported in part by research grant ES-01831 from the National Institute of Environmental Health Sciences, U.S.D.H.H.S. Submitted by Cynthia Hung Stahl in partial fulfillment of the requirements of the University of Texas Health Science Center School of Public Health for a M.Sc. degree in Environmental Science.",

year = "1984",

doi = "10.1016/0742-8413(84)90182-8",

language = "English (US)",

volume = "79",

pages = "177--182",

journal = "Comparative Biochemistry and Physiology. Part C, Comparative",

issn = "0306-4492",

publisher = "Elsevier B.V.",

number = "1",

}

TY - JOUR

T1 - Mixed-function oxidase studies in the redfish, sciaenops ocellata, from galveston bay, texas

AU - Stahl, Cynthia Hung

AU - Sultatos, Lester G.

AU - Hacker, Carl S.

AU - Murphy, Sheldon D.

N1 - Funding Information: ~c~~o~~e~g~~eãu~th-oTrhwse o uldli ke to exprestsh eir appreciatiofonr theh elpg iven by the members of the Texas Department of Parks and Wildlife at Seabrook, Texas, especially Bill Baker. The organisms were collected under the Texas Department of Parks and Wildlife scientific Permit number 86. This work was supported in part by research grant ES-01831 from the National Institute of Environmental Health Sciences, U.S.D.H.H.S. Submitted by Cynthia Hung Stahl in partial fulfillment of the requirements of the University of Texas Health Science Center School of Public Health for a M.Sc. degree in Environmental Science.

PY - 1984

Y1 - 1984

N2 - 1. The metabolism of parathion to para-nitrophenol (PNP) in redfish (Sciaenops ocellata) liver microsomes has been both identified and characterized. 2. This mixed-function oxidase (MFO) reaction in redfish requires NADPH and is inhibited by carbon monoxide. It exhibits a temperature optimum of 25°C but no clear pH optimum between 7.0-8.5. 3. Redfish hepatic microsomal MFOs were not induced by 2.5 days after a single i.p. injection of 88 mg Aroclor 1254/kg body wt, but under the same dosage and time conditions male albino Swiss mice were significantly induced (p < 0.05).

AB - 1. The metabolism of parathion to para-nitrophenol (PNP) in redfish (Sciaenops ocellata) liver microsomes has been both identified and characterized. 2. This mixed-function oxidase (MFO) reaction in redfish requires NADPH and is inhibited by carbon monoxide. It exhibits a temperature optimum of 25°C but no clear pH optimum between 7.0-8.5. 3. Redfish hepatic microsomal MFOs were not induced by 2.5 days after a single i.p. injection of 88 mg Aroclor 1254/kg body wt, but under the same dosage and time conditions male albino Swiss mice were significantly induced (p < 0.05).

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U2 - 10.1016/0742-8413(84)90182-8

DO - 10.1016/0742-8413(84)90182-8

M3 - Article

C2 - 6149864

AN - SCOPUS:0021205305

SN - 0306-4492

VL - 79

SP - 177

EP - 182

JO - Comparative Biochemistry and Physiology. Part C, Comparative

JF - Comparative Biochemistry and Physiology. Part C, Comparative

IS - 1

ER -

Mixed-function oxidase studies in the redfish, sciaenops ocellata, from galveston bay, texas

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