Abstract
A patient with Parkinson's disease had severe levodopa-associated leg pain in a beginning-of-dose and peak-dose pattern. Local anesthetic block of the lumbar sympathetic chain or differential epidural block did not alter the pain. Spinal anesthesia abolished the pain. We postulate that levodopa-associated pain in Parkinson's disease either originates in or is mediated by spinal cord dopaminergic systems.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 171-174 |
| Number of pages | 4 |
| Journal | Clinical Neuropharmacology |
| Volume | 13 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1990 |
All Science Journal Classification (ASJC) codes
- Pharmacology
- Clinical Neurology
- Pharmacology (medical)
Keywords
- Pain
- Parkinson's disease
- Spinal cord
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