Citrifolinin A, a new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of noni (Morinda citrifolia L.)

Shengmin Sang; Kan He; Guangming Liu; Nanqun Zhu; Mingfu Wang; Jin Woo Jhoo; Qunyi Zheng; Zigang Dong; Geetha Ghai; Robert T. Rosen; Chi Tang Ho

doi:10.1016/S0040-4039(01)00018-1

Citrifolinin A, a new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of noni (Morinda citrifolia L.)

Shengmin Sang
, Kan He
, Guangming Liu
, Nanqun Zhu
, Mingfu Wang
, Jin Woo Jhoo
, Qunyi Zheng
, Zigang Dong
, Geetha Ghai
, Robert T. Rosen
, Chi Tang Ho

School of Environmental and Biological Sciences, Food Science

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

A new unusual iridoid, named citrifolinin A, showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, has been isolated from the leaves of Morinda citrifolia. Its structure was elucidated based on a detailed high-field 1D and 2D spectral analysis.

Original language	English (US)
Pages (from-to)	1823-1825
Number of pages	3
Journal	Tetrahedron Letters
Volume	42
Issue number	10
DOIs	https://doi.org/10.1016/S0040-4039(01)00018-1
State	Published - Mar 4 2001

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

Keywords

AP-1
Citrifolinin A
Iridoid
Morinda citrifolia L.
Noni

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10.1016/S0040-4039(01)00018-1

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title = "Citrifolinin A, a new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of noni (Morinda citrifolia L.)",

abstract = "A new unusual iridoid, named citrifolinin A, showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, has been isolated from the leaves of Morinda citrifolia. Its structure was elucidated based on a detailed high-field 1D and 2D spectral analysis.",

keywords = "AP-1, Citrifolinin A, Iridoid, Morinda citrifolia L., Noni",

author = "Shengmin Sang and Kan He and Guangming Liu and Nanqun Zhu and Mingfu Wang and Jhoo, \{Jin Woo\} and Qunyi Zheng and Zigang Dong and Geetha Ghai and Rosen, \{Robert T.\} and Ho, \{Chi Tang\}",

year = "2001",

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doi = "10.1016/S0040-4039(01)00018-1",

language = "English (US)",

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pages = "1823--1825",

journal = "Tetrahedron Letters",

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T1 - Citrifolinin A, a new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of noni (Morinda citrifolia L.)

AU - Sang, Shengmin

AU - He, Kan

AU - Liu, Guangming

AU - Zhu, Nanqun

AU - Wang, Mingfu

AU - Jhoo, Jin Woo

AU - Zheng, Qunyi

AU - Dong, Zigang

AU - Ghai, Geetha

AU - Rosen, Robert T.

AU - Ho, Chi Tang

PY - 2001/3/4

Y1 - 2001/3/4

N2 - A new unusual iridoid, named citrifolinin A, showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, has been isolated from the leaves of Morinda citrifolia. Its structure was elucidated based on a detailed high-field 1D and 2D spectral analysis.

AB - A new unusual iridoid, named citrifolinin A, showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, has been isolated from the leaves of Morinda citrifolia. Its structure was elucidated based on a detailed high-field 1D and 2D spectral analysis.

KW - AP-1

KW - Citrifolinin A

KW - Iridoid

KW - Morinda citrifolia L.

KW - Noni

UR - https://www.scopus.com/pages/publications/0035804474

UR - https://www.scopus.com/pages/publications/0035804474#tab=citedBy

U2 - 10.1016/S0040-4039(01)00018-1

DO - 10.1016/S0040-4039(01)00018-1

M3 - Article

AN - SCOPUS:0035804474

SN - 0040-4039

VL - 42

SP - 1823

EP - 1825

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 10

ER -

Citrifolinin A, a new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of noni (Morinda citrifolia L.)

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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