Abstract
Regression analyses compared 41 type 2 diabetes (T2D) and 131 non-T2D cognitively normal elderly males on the associations of arterial wall function measures [large artery elasticity index (LAEI), small artery elasticity index (SAEI), systemic vascular resistance (SVR), and total vascular impedance (TVI)] with cognitive performance (memory, language, and executive functions), controlling for socio-demographic and cardiovascular factors. Higher LAEI and lower TVI were significantly associated with better executive functions performance in T2D but not in non-T2D subjects. Lower TVI was more associated with better language performance in T2D. Results suggest that arterial wall function is associated with cognition in T2D.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 687-693 |
| Number of pages | 7 |
| Journal | Journal of Alzheimer's Disease |
| Volume | 44 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2015 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- General Neuroscience
- Clinical Psychology
- Geriatrics and Gerontology
- Psychiatry and Mental health
Keywords
- Arterial wall function
- cognitive function
- large artery elasticity index
- total vascular impedance
- type 2 diabetes
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