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Dive into the research topics where Donald Winkelmann is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 6 Finished
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Structural, Biochemical, and Mechanical Effects of Myosin Cardiomyopathy Mutations
Winkelmann, D. (PI), Forgacs, E. (CoPI) & Ostap, M. E. (CoPI)
National Heart, Lung, and Blood Institute
7/1/16 → 4/30/21
Project: Research project
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Molecular Probes of Myosin Structure and Interactions
Winkelmann, D. (PI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases
12/1/93 → 1/31/10
Project: Research project
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MOLECULAR ANALYSIS OF MYOSIN ASSEMBLY
Winkelmann, D. (PI)
National Center for Research Resources
10/1/90 → 9/30/91
Project: Research project
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PROBING MOLECULAR MECHANISM OF MUSCLE CONTRACTION
Winkelmann, D. (PI)
National Center for Research Resources
10/1/87 → 9/30/88
Project: Research project
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MOLECULAR PROBES OF MYOSIN STRUCTURE AND INTERACTIONS
Winkelmann, D. (PI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases
5/1/87 → 4/30/93
Project: Research project
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Mavacamten inhibits myosin activity by stabilizing the myosin interacting-heads motif and stalling motor force generation
Mcmillan, S. N., Pitts, J. R. T., Barua, B., Winkelmann, D. A. & Scarff, C. A., May 29 2026, In: Science Advances. 12, 18, eaea9335.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
A myosin hypertrophic cardiomyopathy mutation disrupts the super-relaxed state and boosts contractility by enhanced actin attachment
Cail, R. C., Barua, B., Báez-Cruz, F. A., Winkelmann, D. A., Goldman, Y. E. & Ostap, E. M., Dec 30 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 52, e2521561122.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Dynamics of β-cardiac myosin between the super-relaxed and disordered-relaxed states
Cail, R. C., Báez-Cruz, F. A., Winkelmann, D. A., Goldman, Y. E. & Ostap, E. M., May 2025, In: Journal of Biological Chemistry. 301, 5, 108412.Research output: Contribution to journal › Article › peer-review
Open Access15 Link opens in a new tab Scopus citations -
S2Tag, a novel affinity tag for the capture and immobilization of coiled-coil proteins: Application to the study of human β-cardiac myosin
Barua, B., Cail, R. C., Goldman, Y. E., Ostap, E. M. & Winkelmann, D. A., Nov 2025, In: Journal of Biological Chemistry. 301, 11, 110776.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Swinging lever mechanism of myosin directly shown by time-resolved cryo-EM
Klebl, D. P., McMillan, S. N., Risi, C., Forgacs, E., Virok, B., Atherton, J. L., Harris, S. A., Stofella, M., Winkelmann, D. A., Sobott, F., Galkin, V. E., Knight, P. J., Muench, S. P., Scarff, C. A. & White, H. D., Jun 12 2025, In: Nature. 642, 8067, p. 519-526 8 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Link opens in a new tab Scopus citations